Early detection

To identify early markers that predict progression to malignant disease and be able to efficiently link it to high risk individuals, we recommend to:

• Critically evaluate currently applied early detection methods and their target populations, and select and promote/disseminate those with proven benefit for broader implementation in the EU.
• Promote biological characterization of premalignant disease that progress to invasive and metastatic cancer.
• Stimulate biomarker discovery and development of diagnostic technologies for early detection of lesions that are likely to progress to cancer.
• Support the development of innovative low-cost devices, methods, and programmes that permit effective early detection with high specificity.
• Develop the concept of prevention screening based on relevant early detection.
• Provide support for their industrial production, testing and validation for use in daily practice.
• Encourage implementation research of early detection programmes, assess participation and analyse factors that affect compliance.
• Analyse clinical effectiveness and health economics of early detection programmes.

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